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In vitro models for liver toxicity testing

Over the years, various liver-derived in vitro model systems have been developed to enable investigation of the potential adverse effects of chemicals and drugs. Liver tissue slices, isolated microsomes, perfused liver, immortalized cell lines, and primary hepatocytes have been used extensively. Imm...

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Detalhes bibliográficos
Main Authors: Soldatow, Valerie Y., LeCluyse, Edward L., Griffith, Linda G., Rusyn, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593300/
https://ncbi.nlm.nih.gov/pubmed/23495363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C2TX20051A
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