EVALUATION OF AN IN VITRO TOXICOGENETIC MOUSE MODEL FOR HEPATOTOXICITY

Numerous studies support the fact that a genetically diverse mouse population may be useful as an animal model to understand and predict toxicity in humans. We hypothesized that cultures of hepatocytes obtained from a large panel of inbred mouse strains can produce data indicative of inter-individua...

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Detalhes bibliográficos
Main Authors: Martinez, Stephanie M., Bradford, Blair U., Soldatow, Valerie Y., Kosyk, Oksana, Sandot, Amelia, Witek, Rafal, Kaiser, Robert, Stewart, Todd, Amaral, Kirsten, Freeman, Kimberly, Black, Chris, LeCluyse, Edward L., Ferguson, Stephen S., Rusyn, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980592/
https://ncbi.nlm.nih.gov/pubmed/20869979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2010.09.012
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