EVALUATION OF AN IN VITRO TOXICOGENETIC MOUSE MODEL FOR HEPATOTOXICITY

Numerous studies support the fact that a genetically diverse mouse population may be useful as an animal model to understand and predict toxicity in humans. We hypothesized that cultures of hepatocytes obtained from a large panel of inbred mouse strains can produce data indicative of inter-individua...

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Autors principals: Martinez, Stephanie M., Bradford, Blair U., Soldatow, Valerie Y., Kosyk, Oksana, Sandot, Amelia, Witek, Rafal, Kaiser, Robert, Stewart, Todd, Amaral, Kirsten, Freeman, Kimberly, Black, Chris, LeCluyse, Edward L., Ferguson, Stephen S., Rusyn, Ivan
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980592/
https://ncbi.nlm.nih.gov/pubmed/20869979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2010.09.012
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