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High-Content Assays for Hepatotoxicity Using Induced Pluripotent Stem Cell–Derived Cells

Development of predictive in vitro assays for early toxicity evaluation is extremely important for improving the drug development process and reducing drug attrition rates during clinical development. High-content imaging-based in vitro toxicity assays are emerging as efficient tools for safety and...

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Detalhes bibliográficos
Main Authors: Sirenko, Oksana, Hesley, Jayne, Rusyn, Ivan, Cromwell, Evan F.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934660/
https://ncbi.nlm.nih.gov/pubmed/24229356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2013.520
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