EVALUATION OF AN IN VITRO TOXICOGENETIC MOUSE MODEL FOR HEPATOTOXICITY

Numerous studies support the fact that a genetically diverse mouse population may be useful as an animal model to understand and predict toxicity in humans. We hypothesized that cultures of hepatocytes obtained from a large panel of inbred mouse strains can produce data indicative of inter-individua...

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Hlavní autoři: Martinez, Stephanie M., Bradford, Blair U., Soldatow, Valerie Y., Kosyk, Oksana, Sandot, Amelia, Witek, Rafal, Kaiser, Robert, Stewart, Todd, Amaral, Kirsten, Freeman, Kimberly, Black, Chris, LeCluyse, Edward L., Ferguson, Stephen S., Rusyn, Ivan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980592/
https://ncbi.nlm.nih.gov/pubmed/20869979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2010.09.012
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