Editor’s Highlight: Modeling Compound-Induced Fibrogenesis In Vitro Using Three-Dimensional Bioprinted Human Liver Tissues

Compound-induced liver injury leading to fibrosis remains a challenge for the development of an Adverse Outcome Pathway useful for human risk assessment. Latency to detection and lack of early, systematically detectable biomarkers make it difficult to characterize the dynamic and complex intercellul...

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Bibliographische Detailangaben
Veröffentlicht in:Toxicol Sci
Hauptverfasser: Norona, Leah M., Nguyen, Deborah G., Gerber, David A., Presnell, Sharon C., LeCluyse, Edward L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
Schlagworte:
In Vitro Fibrogenesis Using 3D Bioprinted Human Liver Tissues
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5139067/
https://ncbi.nlm.nih.gov/pubmed/27605418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw169
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