Database analyses for the prediction of in vivo drug–drug interactions from in vitro data

Por Ito, Kiyomi, Brown, Hayley S, Houston, J Brian
Publicado em 2004

Optimizing drug development: strategies to assess drug metabolism/transporter interaction potential—towards a consensus

Por Tucker, Geoffrey T, Houston, J Brian, Huang, Shiew-Mei
Publicado em 2001

Characterization of In Vitro Glucuronidation Clearance of a Range of Drugs in Human Kidney Microsomes: Comparison with Liver and Intestinal Glucuronidation and Impact of Albumin

Por Gill, Katherine L., Houston, J. Brian, Galetin, Aleksandra
Publicado em 2012

Prediction of in vivo drug–drug interactions from in vitro data: impact of incorporating parallel pathways of drug elimination and inhibitor absorption rate constant

Por Brown, Hayley S, Ito, Kiyomi, Galetin, Aleksandra, Houston, J Brian
Publicado em 2005

In Vitro Assessment of Uptake and Lysosomal Sequestration of Respiratory Drugs in Alveolar Macrophage Cell Line NR8383

Por Ufuk, Ayşe, Somers, Graham, Houston, J. Brian, Galetin, Aleksandra
Publicado no Pharm Res (2015)

Youth’s Reactions to Disasters and the Factors That Influence Their Response

Por Pfefferbaum, Betty, Houston, J. Brian, North, Carol S., Regens, James L.
Publicado em 2008

Simultaneous Assessment of Uptake and Metabolism in Rat Hepatocytes: A Comprehensive Mechanistic Model

Por Ménochet, Karelle, Kenworthy, Kathryn E., Houston, J. Brian, Galetin, Aleksandra
Publicado em 2012

Use of Mechanistic Modeling to Assess Interindividual Variability and Interspecies Differences in Active Uptake in Human and Rat Hepatocytes

Por Ménochet, Karelle, Kenworthy, Kathryn E., Houston, J. Brian, Galetin, Aleksandra
Publicado em 2012

Application of a Physiologically Based Pharmacokinetic Model to Assess Propofol Hepatic and Renal Glucuronidation in Isolation: Utility of In Vitro and In Vivo Data

Por Gill, Katherine L., Gertz, Michael, Houston, J. Brian, Galetin, Aleksandra
Publicado em 2013

Microsomal prediction of in vivo clearance of CYP2C9 substrates in humans

Por Carlile, David J, Hakooz, Nancy, Bayliss, Martin K, Houston, J Brian
Publicado em 1999

Disaster Research Team Building: A Case Study of a Web-based Disaster Research Training Program

Por Beaton, Randal D., Johnson, L. Clark, Maida, Carl A., Houston, J. Brian, Pfefferbaum, Betty
Publicado em 2012

2011 Joplin, Missouri Tornado Experience, Mental Health Reactions, and Service Utilization: Cross-Sectional Assessments at Approximately 6 Months and 2.5 Years Post-Event

Por Houston, J. Brian, Spialek, Matthew L., Stevens, Jordan, First, Jennifer, Mieseler, Vicky L., Pfefferbaum, Betty
Publicado no PLoS Curr (2015)

Assessment of algorithms for predicting drug–drug interactions via inhibition mechanisms: comparison of dynamic and static models

Por Guest, Eleanor J, Rowland-Yeo, Karen, Rostami-Hodjegan, Amin, Tucker, Geoffrey T, Houston, J Brian, Galetin, Aleksandra
Publicado em 2011

Defining the in Vivo Role for Cytochrome b(5) in Cytochrome P450 Function through the Conditional Hepatic Deletion of Microsomal Cytochrome b(5)

Por Finn, Robert D., McLaughlin, Lesley A., Ronseaux, Sebastien, Rosewell, Ian, Houston, J. Brian, Henderson, Colin J., Wolf, C. Roland
Publicado em 2008

Building National Capacity for Child and Family Disaster Mental Health Research

Por Pfefferbaum, Betty, Houston, J. Brian, Reyes, Gilbert, Steinberg, Alan M., Pynoos, Robert S., Fairbank, John A., Brymer, Melissa J., Maida, Carl A.
Publicado em 2010

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of...

Por Godoy, Patricio, Hewitt, Nicola J., Albrecht, Ute, Andersen, Melvin E., Ansari, Nariman, Bhattacharya, Sudin, Bode, Johannes Georg, Bolleyn, Jennifer, Borner, Christoph, Böttger, Jan, Braeuning, Albert, Budinsky, Robert A., Burkhardt, Britta, Cameron, Neil R., Camussi, Giovanni, Cho, Chong-Su, Choi, Yun-Jaie, Craig Rowlands, J., Dahmen, Uta, Damm, Georg, Dirsch, Olaf, Donato, María Teresa, Dong, Jian, Dooley, Steven, Drasdo, Dirk, Eakins, Rowena, Ferreira, Karine Sá, Fonsato, Valentina, Fraczek, Joanna, Gebhardt, Rolf, Gibson, Andrew, Glanemann, Matthias, Goldring, Chris E. P., Gómez-Lechón, María José, Groothuis, Geny M. M., Gustavsson, Lena, Guyot, Christelle, Hallifax, David, Hammad, Seddik, Hayward, Adam, Häussinger, Dieter, Hellerbrand, Claus, Hewitt, Philip, Hoehme, Stefan, Holzhütter, Hermann-Georg, Houston, J. Brian, Hrach, Jens, Ito, Kiyomi, Jaeschke, Hartmut, Keitel, Verena, Kelm, Jens M., Kevin Park, B., Kordes, Claus, Kullak-Ublick, Gerd A., LeCluyse, Edward L., Lu, Peng, Luebke-Wheeler, Jennifer, Lutz, Anna, Maltman, Daniel J., Matz-Soja, Madlen, McMullen, Patrick, Merfort, Irmgard, Messner, Simon, Meyer, Christoph, Mwinyi, Jessica, Naisbitt, Dean J., Nussler, Andreas K., Olinga, Peter, Pampaloni, Francesco, Pi, Jingbo, Pluta, Linda, Przyborski, Stefan A., Ramachandran, Anup, Rogiers, Vera, Rowe, Cliff, Schelcher, Celine, Schmich, Kathrin, Schwarz, Michael, Singh, Bijay, Stelzer, Ernst H. K., Stieger, Bruno, Stöber, Regina, Sugiyama, Yuichi, Tetta, Ciro, Thasler, Wolfgang E., Vanhaecke, Tamara, Vinken, Mathieu, Weiss, Thomas S., Widera, Agata, Woods, Courtney G., Xu, Jinghai James, Yarborough, Kathy M., Hengstler, Jan G.
Publicado em 2013