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Glutathione transferase A4-4 resists adduction by 4-hydroxynonenal

4-Hydroxy-2-trans-nonenal (HNE) is a lipid peroxidation product that contributes to the pathophysiology of several diseases with components of oxidative stress. The electrophilic nature of HNE results in covalent adduct formation with proteins, fatty acids and DNA. However, it remains unclear whethe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shireman, Laura M., Kripps, Kimberly A., Balogh, Larissa M., Conner, Kip P., Whittington, Dale, Atkins, William M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972508/
https://ncbi.nlm.nih.gov/pubmed/20836986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2010.09.005
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