Yüklüyor......
The effect of quinidine, used as a probe for the involvement of P-glycoprotein, on the intestinal absorption and pharmacodynamics of methadone
AIMS: There is considerable unexplained interindividual variability in the methadone dose-effect relationship. The efflux pump P-glycoprotein (P-gp) regulates brain access and intestinal absorption of many drugs. Evidence suggests that methadone is a P-gp substrate in vitro, and P-gp affects methado...
Kaydedildi:
| Asıl Yazarlar: | , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Blackwell Science Inc
2004
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1884496/ https://ncbi.nlm.nih.gov/pubmed/15089813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2003.02053.x |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|