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Translational Assessment of Drug‐Induced Proximal Tubule Injury Using a Kidney Microphysiological System

Drug‐induced kidney injury, a major cause of acute kidney injury, results in progressive kidney disease and is linked to increased mortality in hospitalized patients. Primary injury sites of drug‐induced kidney injury are proximal tubules. Clinically, kidney injury molecule‐1, an established tubule‐...

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Detalhes bibliográficos
Publicado no:CPT Pharmacometrics Syst Pharmacol
Main Authors: Maass, Christian, Sorensen, Nathan B., Himmelfarb, Jonathan, Kelly, Edward J., Stokes, Cynthia L., Cirit, Murat
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6539699/
https://ncbi.nlm.nih.gov/pubmed/30869201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12400
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