Translational Assessment of Drug‐Induced Proximal Tubule Injury Using a Kidney Microphysiological System

Drug‐induced kidney injury, a major cause of acute kidney injury, results in progressive kidney disease and is linked to increased mortality in hospitalized patients. Primary injury sites of drug‐induced kidney injury are proximal tubules. Clinically, kidney injury molecule‐1, an established tubule‐...

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Foilsithe in:CPT Pharmacometrics Syst Pharmacol
Main Authors: Maass, Christian, Sorensen, Nathan B., Himmelfarb, Jonathan, Kelly, Edward J., Stokes, Cynthia L., Cirit, Murat
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2019
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6539699/
https://ncbi.nlm.nih.gov/pubmed/30869201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12400
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