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Finding Homes for Orphan Cytochrome P450s: CYP4V2 and CYP4F22 in Disease States

Genetic analyses have identified a wide spectrum of mutations in the CYP4V2 gene from patients suffering from Bietti’s crystalline corneoretinal dystrophy, and mutations in the CYP4F22 gene have been linked to lamellar ichthyosis. These strong gene–disease associations will be better understood if w...

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Detalhes bibliográficos
Main Authors: Kelly, Edward J., Nakano, Mariko, Rohatgi, Priyanka, Yarov-Yarovoy, Vladimir, Rettie, Allan E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Pharmacology and Experimental Therapeutics 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109859/
https://ncbi.nlm.nih.gov/pubmed/21540472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mi.11.2.10
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