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Expression and Characterization of CYP4V2 as a Fatty Acid ω-Hydroxylase

Bietti's crystalline dystrophy is an ocular disease that is strongly associated with polymorphisms in the CYP4V2 gene. CYP4 enzymes are typically microsomal fatty acid ω-hydroxylases that function together with mitochondrial and peroxisomal β-oxidation enzymes to degrade cellular lipids. Indeed...

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Detalhes bibliográficos
Main Authors: Nakano, Mariko, Kelly, Edward J., Rettie, Allan E.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774980/
https://ncbi.nlm.nih.gov/pubmed/19661213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.109.028530
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