Cytochrome P450-Dependent Catabolism of Vitamin K: ω-Hydroxylation Catalyzed by Human CYP4F2 and CYP4F11

Vitamin K plays an essential role in many biological processes including blood clotting, maintenance of bone health, and inhibition of arterial calcification. A menaquinone form of vitamin K, MK4, is increasingly recognized for its key roles in mitochondrial electron transport, as a ligand for the n...

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Hauptverfasser: Edson, Katheryne Z., Prasad, Bhagwat, Unadkat, Jashvant D., Suhara, Yoshitomo, Okano, Toshio, Guengerich, F. Peter, Rettie, Allan E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900248/
https://ncbi.nlm.nih.gov/pubmed/24138531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi401208m
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