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ω-Hydroxylation of phylloquinone by CYP4F2 is not increased by α-tocopherol
SCOPE: The objective of this study was to investigate the initial catabolic step of vitamin E and K metabolism, the ω-hydroxylation by human cytochrome P450 4F2 (CYP4F2). METHODS AND RESULTS: Tocopherol (T) metabolism was compared using rat liver slices incubated with deuterated (d(6))-RRR-α-T (d(6)...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3833818/ https://ncbi.nlm.nih.gov/pubmed/23650179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201200797 |
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