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Deuterium-labeled Phylloquinone Fed to α-Tocopherol Injected Rats Demonstrates Sensitivity of Low Phylloquinone-Containing Tissues to Menaquinone-4 Depletion
The influence of excess α-tocopherol (α-T) on tissue depletion of phylloquinone (PK) and menaquinone-4 (MK-4) was evaluated by feeding rats (n=5/group) deuterium-labeled-PK (d(4)-PK, 2 µmol/kg) for 17 d, thereby labeling the conversion from d(4)-PK to d(4)-MK-4. Then they were injected subcutaneousl...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4183557/ https://ncbi.nlm.nih.gov/pubmed/25044667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201300659 |
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