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Development and characterization of transgenic mouse models for conditional gene knockout in the blood–brain and blood-CSF barriers
For many CNS acting drugs, penetration into the central nervous system (CNS) is limited by the blood-CNS-barriers. In an effort to quantitate the role of the protein components that make up the blood-CNS-barriers, we created transgenic mice that allow conditional gene knockout using Cre/loxP technol...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3192922/ https://ncbi.nlm.nih.gov/pubmed/21538071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11248-011-9512-z |
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