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Role of the Breast Cancer Resistance Protein (BCRP/ABCG2) in Drug Transport—an Update

The human breast cancer resistance protein (BCRP, gene symbol ABCG2) is an ATP-binding cassette (ABC) efflux transporter. It was so named because it was initially cloned from a multidrug-resistant breast cancer cell line where it was found to confer resistance to chemotherapeutic agents such as mito...

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Detalhes bibliográficos
Publicado no:AAPS J
Main Authors: Mao, Qingcheng, Unadkat, Jashvant D.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287283/
https://ncbi.nlm.nih.gov/pubmed/25236865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-014-9668-6
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