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Multiple Computational Approaches for Predicting Drug Interactions with Human Equilibrative Nucleoside Transporter 1

Equilibrativenucleoside transporters (ENTs) participate in the pharmacokinetics and disposition of nucleoside analog drugs. Understanding drug interactions with the ENTs may inform and facilitate the development of new drugs, including chemotherapeutics and antivirals that require access to sanctuar...

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Detalhes bibliográficos
Publicado no:Drug Metab Dispos
Main Authors: Miller, Siennah R., Lane, Thomas R., Zorn, Kimberley M., Ekins, Sean, Wright, Stephen H., Cherrington, Nathan J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8313052/
https://ncbi.nlm.nih.gov/pubmed/33980604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.121.000423
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