Testicular disposition of clofarabine in rats is dependent on equilibrative nucleoside transporters

Acute lymphoblastic leukemia (ALL) is the most common cancer in children and adolescents. Although the 5‐year survival rate is high, some patients respond poorly to chemotherapy or have recurrence in locations such as the testis. The blood–testis barrier (BTB) can prevent complete eradication by lim...

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Veröffentlicht in:Pharmacol Res Perspect
Hauptverfasser: Miller, Siennah R., Jilek, Joseph L., McGrath, Meghan E., Hau, Raymond K., Jennings, Erin Q., Galligan, James J., Wright, Stephen H., Cherrington, Nathan J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2021
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8292784/
https://ncbi.nlm.nih.gov/pubmed/34288585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.831
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