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Multiple Computational Approaches for Predicting Drug Interactions with Human Equilibrative Nucleoside Transporter 1

Equilibrativenucleoside transporters (ENTs) participate in the pharmacokinetics and disposition of nucleoside analog drugs. Understanding drug interactions with the ENTs may inform and facilitate the development of new drugs, including chemotherapeutics and antivirals that require access to sanctuar...

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Détails bibliographiques
Publié dans:Drug Metab Dispos
Auteurs principaux: Miller, Siennah R., Lane, Thomas R., Zorn, Kimberley M., Ekins, Sean, Wright, Stephen H., Cherrington, Nathan J.
Format: Artigo
Langue:Inglês
Publié: The American Society for Pharmacology and Experimental Therapeutics 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8313052/
https://ncbi.nlm.nih.gov/pubmed/33980604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.121.000423
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