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Modeling Human Nonalcoholic Steatohepatitis-Associated Changes in Drug Transporter Expression Using Experimental Rodent Models

Nonalcoholic fatty liver disease is a prevalent form of chronic liver disease that can progress to the more advanced stage of nonalcoholic steatohepatitis (NASH). NASH has been shown to alter drug transporter regulation and may have implications in the development of adverse drug reactions. Several...

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Главные авторы: Canet, Mark J., Hardwick, Rhiannon N., Lake, April D., Dzierlenga, Anika L., Clarke, John D., Cherrington, Nathan J.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Pharmacology and Experimental Therapeutics 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965900/
https://ncbi.nlm.nih.gov/pubmed/24384915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.113.055996
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