Genetics or environment in drug transport: the case of organic anion transporting polypeptides and adverse drug reactions

מאת Clarke, John D, Cherrington, Nathan J
יצא לאור 2012

Nonalcoholic Steatohepatitis in Precision Medicine: Unraveling the Factors that Contribute to Individual Variability

מאת Clarke, John D., Cherrington, Nathan J.
הוצא לאור ב Pharmacol Ther (2015)

Multi-targeted prevention of cancer by sulforaphane

מאת Clarke, John D., Dashwood, Roderick H., Ho, Emily
יצא לאור 2008

Dietary Sulforaphane, a Histone Deacetylase Inhibitor for Cancer Prevention

מאת Ho, Emily, Clarke, John D., Dashwood, Roderick H.
יצא לאור 2009

Sub-chronic microcystin-LR renal toxicity in rats fed a high fat/high cholesterol diet

מאת Arman, Tarana, Lynch, Katherine D., Goedken, Michael, Clarke, John D.
הוצא לאור ב Chemosphere (2020)

Differential effects of sulforaphane on histone deacetylases, cell cycle arrest and apoptosis in normal prostate cells versus hyperplastic and cancerous prostate cells

מאת Clarke, John D., Hsu, Anna, Yu, Zhen, Dashwood, Roderick H., Ho, Emily
יצא לאור 2011

Interaction of Oatp1b2 Expression and Nonalcoholic Steatohepatitis on Pravastatin Plasma Clearance

מאת Toth, Erica L., Clarke, John D., Csanaky, Iván L., Cherrington, Nathan J.
הוצא לאור ב Biochem Pharmacol (2019)

Sub-Chronic Microcystin-LR Liver Toxicity in Preexisting Diet-Induced Nonalcoholic Steatohepatitis in Rats

מאת Arman, Tarana, Lynch, Katherine D., Montonye, Michelle L., Goedken, Michael, Clarke, John D.
הוצא לאור ב Toxins (Basel) (2019)

Selective and Cytokine-Dependent Regulation of Hepatic Transporters and Bile Acid Homeostasis during Infectious Colitis in Mice

מאת Merrell, Matthew D., Nyagode, Beatrice A., Clarke, John D., Cherrington, Nathan J., Morgan, Edward T.
יצא לאור 2014

Impaired N-linked Glycosylation of Uptake and Efflux Transporters in Human Nonalcoholic Fatty Liver Disease

מאת Clarke, John D, Novak, Petr, Lake, April D, Hardwick, Rhiannon N, Cherrington, Nathan J
הוצא לאור ב Liver Int (2017)

Comparison of isothiocyanate metabolite levels and histone deacetylase activity in human subjects consuming broccoli sprouts or broccoli supplement

מאת Clarke, John D., Riedl, Ken, Bella, Deborah, Schwartz, Steven J., Stevens, Jan F., Ho, Emily
יצא לאור 2011

Experimental Nonalcoholic Steatohepatitis Increases Exposure to Simvastatin Hydroxy Acid by Decreasing Hepatic Organic Anion Transporting Polypeptide Expression

מאת Clarke, John D., Hardwick, Rhiannon N., Lake, April D., Canet, Mark J., Cherrington, Nathan J.
יצא לאור 2014

Circulating microRNA 122 in the Methionine and Choline Deficient Mouse Model of Nonalcoholic Steatohepatitis

מאת Clarke, John D., Sharapova, Tatiana, Lake, April D., Blomme, Eric, Maher, Jonathan, Cherrington, Nathan J.
יצא לאור 2013

Metabolism and tissue distribution of sulforaphane in Nrf2 knockout and wild-type mice

מאת Clarke, John D., Hsu, Anna, Williams, David E., Dashwood, Roderick H., Stevens, Jan F., Ho, Emily
יצא לאור 2011

In vivo cytochrome P450 activity alterations in diabetic nonalcoholic steatohepatitis mice

מאת Li, Hui, Clarke, John D., Dzierlenga, Anika L., Bear, John, Goedken, Michael J., Cherrington, Nathan J.
הוצא לאור ב J Biochem Mol Toxicol (2016)

Bioavailability and inter-conversion of sulforaphane and erucin in human subjects consuming broccoli sprouts or broccoli supplement in a cross-over study design

מאת Clarke, John D., Hsu, Anna, Riedl, Ken, Bella, Deborah, Schwartz, Steven J., Stevens, Jan F., Ho, Emily
יצא לאור 2011

Modeling Human Nonalcoholic Steatohepatitis-Associated Changes in Drug Transporter Expression Using Experimental Rodent Models

מאת Canet, Mark J., Hardwick, Rhiannon N., Lake, April D., Dzierlenga, Anika L., Clarke, John D., Cherrington, Nathan J.
יצא לאור 2014

Gene-by-Environment Interaction of Bcrp(−/−) and Methionine- and Choline-Deficient Diet–Induced Nonalcoholic Steatohepatitis Alters SN-38 Disposition

מאת Toth, Erica L., Li, Hui, Dzierlenga, Anika L., Clarke, John D., Vildhede, Anna, Goedken, Michael, Cherrington, Nathan J.
הוצא לאור ב Drug Metab Dispos (2018)

Mechanism of Altered Metformin Distribution in Nonalcoholic Steatohepatitis

מאת Clarke, John D., Dzierlenga, Anika L., Nelson, Nicholas R., Li, Hui, Werts, Samantha, Goedken, Michael J., Cherrington, Nathan J.
הוצא לאור ב Diabetes (2015)

A Pharmacokinetic Natural Product-Disease-Drug Interaction: A Double Hit of Silymarin and Nonalcoholic Steatohepatitis on Hepatic Transporters in a Rat Model

מאת Montonye, Michelle L., Tian, Dan-Dan, Arman, Tarana, Lynch, Katherine D., Hagenbuch, Bruno, Paine, Mary F., Clarke, John D.
הוצא לאור ב J Pharmacol Exp Ther (2019)