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Metabolism and tissue distribution of sulforaphane in Nrf2 knockout and wild-type mice

PURPOSE: To determine the metabolism and tissue distribution of the dietary chemoprotective agent sulforaphane following oral administration to wild-type and Nrf2 knockout (Nrf2(−/−)) mice. METHODS: Male and female wild-type and Nrf2(−/−) mice were given sulforaphane (5 or 20 µmoles) by oral gavage,...

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Detalhes bibliográficos
Main Authors: Clarke, John D., Hsu, Anna, Williams, David E., Dashwood, Roderick H., Stevens, Jan F., Ho, Emily
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253624/
https://ncbi.nlm.nih.gov/pubmed/21681606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-011-0500-z
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