Loading...

Differential effects of sulforaphane on histone deacetylases, cell cycle arrest and apoptosis in normal prostate cells versus hyperplastic and cancerous prostate cells

Sulforaphane (SFN) is an isothiocyanate derived from cruciferous vegetables such as broccoli. The ability of SFN to inhibit histone deacetylase enzymes may be one mechanism by which it acts as a chemoprevention agent. The ability of a chemopreventive agent to specifically cause cytotoxicity in cance...

Full description

Saved in:
Bibliographic Details
Main Authors: Clarke, John D., Hsu, Anna, Yu, Zhen, Dashwood, Roderick H., Ho, Emily
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129466/
https://ncbi.nlm.nih.gov/pubmed/21374800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201000547
Tags: Add Tag
No Tags, Be the first to tag this record!