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Differential effects of sulforaphane on histone deacetylases, cell cycle arrest and apoptosis in normal prostate cells versus hyperplastic and cancerous prostate cells

Sulforaphane (SFN) is an isothiocyanate derived from cruciferous vegetables such as broccoli. The ability of SFN to inhibit histone deacetylase enzymes may be one mechanism by which it acts as a chemoprevention agent. The ability of a chemopreventive agent to specifically cause cytotoxicity in cance...

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Bibliografiska uppgifter
Huvudupphovsmän: Clarke, John D., Hsu, Anna, Yu, Zhen, Dashwood, Roderick H., Ho, Emily
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129466/
https://ncbi.nlm.nih.gov/pubmed/21374800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201000547
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