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Green tea polyphenols causes cell cycle arrest and apoptosis in prostate cancer cells by suppressing class I histone deacetylases

Green tea polyphenols (GTPs) reactivate epigenetically silenced genes in cancer cells and trigger cell cycle arrest and apoptosis; however, the mechanisms whereby these effects occur are not well understood. We investigated the molecular mechanisms underlying the antiproliferative effects of GTP, wh...

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Detalhes bibliográficos
Main Authors: Thakur, Vijay S., Gupta, Karishma, Gupta, Sanjay
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499108/
https://ncbi.nlm.nih.gov/pubmed/22114073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr277
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