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Green Tea Polyphenols Induce p53-Dependent and p53-Independent Apoptosis in Prostate Cancer Cells through Two Distinct Mechanisms

Inactivation of the tumor suppressor gene p53 is commonly observed in human prostate cancer and is associated with therapeutic resistance. We have previously demonstrated that green tea polyphenols (GTP) induce apoptosis in prostate cancer cells irrespective of p53 status. However, the molecular mec...

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Detalhes bibliográficos
Main Authors: Gupta, Karishma, Thakur, Vijay S., Bhaskaran, Natarajan, Nawab, Akbar, Babcook, Melissa A., Jackson, Mark W., Gupta, Sanjay
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527608/
https://ncbi.nlm.nih.gov/pubmed/23285096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052572
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