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Genetics or environment in drug transport: the case of organic anion transporting polypeptides and adverse drug reactions
INTRODUCTION: Organic anion transporting polypeptide (OATP) uptake transporters are important for the disposition of many drugs and perturbed OATP activity can contribute to adverse drug reactions (ADRs). It is well documented that both genetic and environmental factors can alter OATP expression and...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3753226/ https://ncbi.nlm.nih.gov/pubmed/22280100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17425255.2012.656087 |
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