Quantitative-Profiling of Bile Acids and their Conjugates in Mouse Liver, Bile, Plasma, and Urine Using LC-MS/MS

Por Alnouti, Yazen, Csanaky, Iván L., Klaassen, Curtis D.
Publicado em 2008

Gender-Divergent Profile of Bile Acid Homeostasis during Aging of Mice

Por Fu, Zidong Donna, Csanaky, Iván L., Klaassen, Curtis D.
Publicado em 2012

Effects of Aging on mRNA Profiles for Drug-Metabolizing Enzymes and Transporters in Livers of Male and Female Mice

Por Fu, Zidong Donna, Csanaky, Iván L., Klaassen, Curtis D.
Publicado em 2012

Calorie Restriction Increases P-Glycoprotein and Decreases Intestinal Absorption of Digoxin in Mice

Por Renaud, Helen J., Klaassen, Curtis D., Csanaky, Iván L.
Publicado no Drug Metab Dispos (2016)

Role of hepatic transporters in prevention of bile acid toxicity after partial hepatectomy in mice

Por Csanaky, Iván L., Aleksunes, Lauren M., Tanaka, Yuji, Klaassen, Curtis D.
Publicado em 2009

Importance of Large Intestine in Regulating Bile Acids and Glucagon-Like Peptide-1 in Germ-Free Mice

Por Selwyn, Felcy Pavithra, Csanaky, Iván L., Zhang, Youcai, Klaassen, Curtis D.
Publicado no Drug Metab Dispos (2015)

Nrf2 Activation Enhances Biliary Excretion of Sulfobromophthalein by Inducing Glutathione-S-Transferase Activity

Por Reisman, Scott A., Csanaky, Iván L., Yeager, Ronnie L., Klaassen, Curtis D.
Publicado em 2009

Altered Disposition of Acetaminophen in Nrf2-null and Keap1-knockdown Mice

Por Reisman, Scott A., Csanaky, Iván L., Aleksunes, Lauren M., Klaassen, Curtis D.
Publicado em 2009

Multidrug Resistance-Associated Protein 3 Plays an Important Role in Protection against Acute Toxicity of Diclofenac

Por Scialis, Renato J., Csanaky, Iván L., Goedken, Michael J., Manautou, José E.
Publicado no Drug Metab Dispos (2015)

Activation of Constitutive Androstane Receptor (CAR) in Mice Results in Maintained Biliary Excretion of Bile Acids Despite a Marked Decrease of Bile Acids in Liver

Por Lickteig, Andrew J., Csanaky, Iván L., Pratt-Hyatt, Matthew, Klaassen, Curtis D.
Publicado no Toxicol Sci (2016)

Loss of Organic Anion Transporting Polypeptide 1a1 Increases Deoxycholic Acid Absorption in Mice by Increasing Intestinal Permeability

Por Zhang, Youcai, Csanaky, Iván L., Lehman-McKeeman, Lois D., Klaassen, Curtis D.
Publicado em 2011

Organic Anion–Transporting Polypeptide 1b2 (Oatp1b2) Is Important for the Hepatic Uptake of Unconjugated Bile Acids: Studies in Oatp1b2-Null Mice

Por Csanaky, Iván L., Lu, Hong, Zhang, Youcai, Ogura, Kenichiro, Choudhuri, Supratim, Klaassen, Curtis D.
Publicado em 2010

Organic Anion Transporting Polypeptide 1a1 Null Mice Are Sensitive to Cholestatic Liver Injury

Por Zhang, Youcai, Csanaky, Iván L., Cheng, Xingguo, Lehman-McKeeman, Lois D., Klaassen, Curtis D.
Publicado em 2012

Organic anion-transporting polypeptide 1a4 (Oatp1a4) is important for secondary bile acid metabolism

Por Zhang, Youcai, Csanaky, Iván L., Selwyn, Felcy Pavithra, Lehman-McKeeman, Lois D., Klaassen, Curtis D.
Publicado em 2013

Characterization of Organic Anion Transporting Polypeptide 1b2-null Mice: Essential Role in Hepatic Uptake/Toxicity of Phalloidin and Microcystin-LR

Por Lu, Hong, Choudhuri, Supratim, Ogura, Kenichiro, Csanaky, Iván L., Lei, Xiaohong, Cheng, Xingguo, Song, Pei-zhen, Klaassen, Curtis D.
Publicado em 2008

Human PXR modulates hepatotoxicity associated with rifampicin and isoniazid co–therapy

Por Li, Feng, Lu, Jie, Cheng, Jie, Wang, Laiyou, Matsubara, Tsutomu, Csanaky, Iván L., Klaassen, Curtis D., Gonzalez, Frank J., Ma, Xiaochao
Publicado em 2013

Gender-specific reduction of hepatic Mrp2 expression by high-fat diet protects female mice from ANIT toxicity

Por Kong, Bo, Csanaky, Iván L., Aleksunes, Lauren M., Patni, Meghan, Chen, Qi, Ma, Xiaochao, Jaeschke, Hartmut, Weir, Scott, Broward, Melinda, Klaassen, Curtis D., Guo, Grace L.
Publicado em 2012

H1-antihistamines exacerbate high-fat diet-induced hepatic steatosis in wild-type but not in apolipoprotein E knockout mice

Por Raveendran, Vineesh V., Kassel, Karen M., Smith, Donald D., Luyendyk, James P., Williams, Kurt J., Cherian, Rachel, Reed, Gregory A., Flynn, Colleen A., Csanaky, Iván L., Lickteig, Andrew L., Pratt-Hyatt, Matthew J., Klaassen, Curtis D., Dileepan, Kottarappat N.
Publicado em 2014