Organic Anion–Transporting Polypeptide 1b2 (Oatp1b2) Is Important for the Hepatic Uptake of Unconjugated Bile Acids: Studies in Oatp1b2-Null Mice

The organic anion–transporting polypeptide 1b family (Oatp1b2 in rodents and OATP1B1/1B3 in humans) is liver-specific and transports various chemicals into the liver. However, the role of the Oatp1b family in the hepatic uptake of bile acids (BAs) into the liver is unknown. Therefore, in Oatp1b2-nul...

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Bibliographic Details
Main Authors: Csanaky, Iván L., Lu, Hong, Zhang, Youcai, Ogura, Kenichiro, Choudhuri, Supratim, Klaassen, Curtis D.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186067/
https://ncbi.nlm.nih.gov/pubmed/20949553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23984
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