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Preference of Conjugated Bile Acids over Unconjugated Bile Acids as Substrates for OATP1B1 and OATP1B3

Bile acids, the metabolites of cholesterol, are signaling molecules that play critical role in many physiological functions. They undergo enterohepatic circulation through various transporters expressed in intestine and liver. Human organic anion-transporting polypeptides (OATP) 1B1 and OATP1B3 cont...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Suga, Takahiro, Yamaguchi, Hiroaki, Sato, Toshihiro, Maekawa, Masamitsu, Goto, Junichi, Mano, Nariyasu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5218478/
https://ncbi.nlm.nih.gov/pubmed/28060902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169719
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