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Organic Anion Transporting Polypeptide 1a1 Null Mice Are Sensitive to Cholestatic Liver Injury

Organic anion transporting polypeptide 1a1 (Oatp1a1) is predominantly expressed in livers of mice and is thought to transport bile acids (BAs) from blood into liver. Because Oatp1a1 expression is markedly decreased in mice after bile duct ligation (BDL). We hypothesized that Oatp1a1-null mice would...

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Main Authors: Zhang, Youcai, Csanaky, Iván L., Cheng, Xingguo, Lehman-McKeeman, Lois D., Klaassen, Curtis D.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355319/
https://ncbi.nlm.nih.gov/pubmed/22461449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs123
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