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Calorie Restriction Increases P-Glycoprotein and Decreases Intestinal Absorption of Digoxin in Mice

There is wide variation in how patients respond to therapeutics. Factors that contribute to pharmacokinetic variations include disease, genetics, drugs, age, and diet. The purpose of this study was to determine the effect of calorie restriction on the expression of Abcb1a in the intestine and whethe...

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Detaylı Bibliyografya
Yayımlandı:Drug Metab Dispos
Asıl Yazarlar: Renaud, Helen J., Klaassen, Curtis D., Csanaky, Iván L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Pharmacology and Experimental Therapeutics 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767382/
https://ncbi.nlm.nih.gov/pubmed/26744253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.064766
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