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Editor’s Highlight: Clofibrate Decreases Bile Acids in Livers of Male Mice by Increasing Biliary Bile Acid Excretion in a PPARα-Dependent Manner

Fibrates and their receptor, namely peroxisome proliferator-activated receptor α (PPARα), have been reported to regulate bile acid (BA) synthesis and transport. However, the effect of fibrate treatment and PPARα activation on BA homeostasis remains controversial. In this study, both wild-type (WT) a...

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Publicat a:Toxicol Sci
Autors principals: Zhang, Youcai, Lickteig, Andrew J, Csanaky, Iván L, Klaassen, Curtis D
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837458/
https://ncbi.nlm.nih.gov/pubmed/28973556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfx191
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