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Activation of PPARα decreases bile acids in livers of female mice while maintaining bile flow and biliary bile acid excretion
Fibrates are hypolipidemic drugs that act as activators of peroxisome proliferator-activated receptor α (PPARα). In both humans and rodents, females were reported to be less responsive to fibrates than males. Previous studies on fibrates and PPARα usually involved male mice, but little has been done...
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| Publicado no: | Toxicol Appl Pharmacol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5915336/ https://ncbi.nlm.nih.gov/pubmed/29175453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2017.11.014 |
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