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Effects of ablation and activation of Nrf2 on bile acid homeostasis in mice

Increasing evidence suggests that nuclear factor erythroid 2-related factor 2 (Nrf2) is a promising therapeutic target in cholestasis. However, the role of Nrf2 in bile acid (BA) homeostasis remains controversial. In this study, activation of Nrf2 was achieved either pharmacologically by CDDO-imidaz...

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Detaylı Bibliyografya
Yayımlandı:Toxicol Appl Pharmacol
Asıl Yazarlar: Zhang, Youcai, Lickteig, Andrew J., Liu, Jing, Csanaky, Iván L., Klaassen, Curtis D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7489283/
https://ncbi.nlm.nih.gov/pubmed/32738332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2020.115170
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