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Effects of ablation and activation of Nrf2 on bile acid homeostasis in mice
Increasing evidence suggests that nuclear factor erythroid 2-related factor 2 (Nrf2) is a promising therapeutic target in cholestasis. However, the role of Nrf2 in bile acid (BA) homeostasis remains controversial. In this study, activation of Nrf2 was achieved either pharmacologically by CDDO-imidaz...
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| Publicado no: | Toxicol Appl Pharmacol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7489283/ https://ncbi.nlm.nih.gov/pubmed/32738332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2020.115170 |
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