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In vivo cytochrome P450 activity alterations in diabetic nonalcoholic steatohepatitis mice
Nonalcoholic steatohepatitis (NASH) has been identified as a source of significant interindividual variation in drug metabolism. A previous ex vivo study demonstrated significant changes in hepatic Cytochrome P450 (CYP) activity in human NASH. This study evaluated the in vivo activities of multiple...
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| Publié dans: | J Biochem Mol Toxicol |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5426479/ https://ncbi.nlm.nih.gov/pubmed/27712037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbt.21840 |
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