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Modeling Human Nonalcoholic Steatohepatitis-Associated Changes in Drug Transporter Expression Using Experimental Rodent Models

Nonalcoholic fatty liver disease is a prevalent form of chronic liver disease that can progress to the more advanced stage of nonalcoholic steatohepatitis (NASH). NASH has been shown to alter drug transporter regulation and may have implications in the development of adverse drug reactions. Several...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Canet, Mark J., Hardwick, Rhiannon N., Lake, April D., Dzierlenga, Anika L., Clarke, John D., Cherrington, Nathan J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965900/
https://ncbi.nlm.nih.gov/pubmed/24384915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.113.055996
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