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Synergistic interaction between genetics and disease on pravastatin disposition
BACKGROUND & AIMS: A genome wide association study and multiple pharmacogenetic studies have implicated the hepatic uptake transporter organic anion transporting polypeptide-1B1 (OATP1B1) in the pharmacokinetics and musculoskeletal toxicity of statin drugs. Other OATP uptake transporters can par...
Bewaard in:
Hoofdauteurs: | , , , , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
2014
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4065643/ https://ncbi.nlm.nih.gov/pubmed/24613363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2014.02.021 |
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