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Nuclear Factor Erythroid 2-Related Factor 2 Deletion Impairs Glucose Tolerance and Exacerbates Hyperglycemia in Type 1 Diabetic Mice

The transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) induces a battery of cytoprotective genes after oxidative stress. Nrf2 aids in liver regeneration by altering insulin signaling; however, whether Nrf2 participates in hepatic glucose homeostasis is unknown. Compared with wil...

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Bibliografische gegevens
Hoofdauteurs: Aleksunes, Lauren M., Reisman, Scott A., Yeager, Ronnie L., Goedken, Michael J., Klaassen, Curtis D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Pharmacology and Experimental Therapeutics 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846027/
https://ncbi.nlm.nih.gov/pubmed/20086057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.162271
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