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Effect of allyl alcohol on hepatic transporter expression: Zonal patterns of expression and role of Kupffer cell function

During APAP toxicity, activation of Kupffer cells is critical for protection from hepatotoxicity and up-regulation of multidrug resistance-associated protein 4 (Mrp4) in centrilobular hepatocytes. The present study was performed to determine the expression profile of uptake and efflux transporters i...

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Publicat a:Toxicol Appl Pharmacol
Autors principals: Campion, Sarah N., Tatis-Rios, Cristina, Augustine, Lisa M., Goedken, Michael J., van Rooijen, Nico, Cherrington, Nathan J., Manautou, José E.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404030/
https://ncbi.nlm.nih.gov/pubmed/19371622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2009.01.007
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