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Hepatic Mrp4 induction following acetaminophen exposure is dependent on Kupffer cell function
During acetaminophen (APAP) hepatotoxicity, increased expression of multidrug resistance-associated proteins 2, 3, and 4 (Mrp2-4) occurs. Mrp4 is the most significantly upregulated transporter in mouse liver following APAP treatment. Although the expression profiles of liver transporters following A...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2519859/ https://ncbi.nlm.nih.gov/pubmed/18556419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00541.2007 |
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