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MDR1 Transporter Protects Against Paraquat-Induced Toxicity in Human and Mouse Proximal Tubule Cells

Paraquat is a herbicide that is highly toxic to the lungs and kidneys following acute exposures. Prior studies have demonstrated that the organic cation transporter 2 and multidrug and toxin extrusion protein 1 contribute to the urinary secretion of paraquat in the kidneys. The purpose of this study...

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Publicado en:Toxicol Sci
Autores principales: Wen, Xia, Gibson, Christopher J., Yang, Ill, Buckley, Brian, Goedken, Michael J., Richardson, Jason R., Aleksunes, Lauren M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2014
Materias:
116
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271045/
https://ncbi.nlm.nih.gov/pubmed/25015657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu141
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