Disruption of the Lcn2 gene in mice suppresses primary mammary tumor formation but does not decrease lung metastasis

por Berger, Thorsten, Cheung, Carol C., Elia, Andrew J., Mak, Tak W.
Publicado 2010

Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development

por Ueda, Takeshi, Sasaki, Masato, Elia, Andrew J., Chio, Iok In Christine, Hamada, Koichi, Fukunaga, Rikiro, Mak, Tak W.
Publicado 2010

Retinoblastoma tumor suppressor protein in pancreatic progenitors controls α- and β-cell fate

por Cai, Erica P., Wu, Xiaohong, Schroer, Stephanie A., Elia, Andrew J., Nostro, M. Cristina, Zacksenhaus, Eldad, Woo, Minna
Publicado 2013

Tumor Necrosis Factor Receptor-Associated Factor 6 (TRAF6) Deficiency Results in Exencephaly and Is Required for Apoptosis within the Developing CNS

por Lomaga, Mark A., Henderson, Jeffrey T., Elia, Andrew J., Robertson, Jennifer, Noyce, Ryan S., Yeh, Wen-Chen, Mak, Tak W.
Publicado en J Neurosci (2000)

Severe liver degeneration and lack of NF-κB activation in NEMO/IKKγ-deficient mice

por Rudolph, Dorothea, Yeh, Wen-Chen, Wakeham, Andrew, Rudolph, Bettina, Nallainathan, Dhani, Potter, Julia, Elia, Andrew J., Mak, Tak W.
Publicado 2000

Hypoxia-inducible factor 1 alpha limits dendritic cell stimulation of CD8 T cell immunity

por Tran, Charles W., Gold, Matthew J., Garcia-Batres, Carlos, Tai, Kelly, Elford, Alisha R., Himmel, Megan E., Elia, Andrew J., Ohashi, Pamela S.
Publicado en PLoS One (2020)

Lipocalin 2-deficient mice exhibit increased sensitivity to Escherichia coli infection but not to ischemia-reperfusion injury

por Berger, Thorsten, Togawa, Atsushi, Duncan, Gordon S., Elia, Andrew J., You-Ten, Annick, Wakeham, Andrew, Fong, Hannah E. H., Cheung, Carol C., Mak, Tak W.
Publicado 2006

Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells

por Hitoshi, Seiji, Alexson, Tania, Tropepe, Vincent, Donoviel, Dorit, Elia, Andrew J., Nye, Jeffrey S., Conlon, Ronald A., Mak, Tak W., Bernstein, Alan, van der Kooy, Derek
Publicado 2002

Smg1 is required for embryogenesis and regulates diverse genes via alternative splicing coupled to nonsense-mediated mRNA decay

por McIlwain, David R., Pan, Qun, Reilly, Patrick T., Elia, Andrew J., McCracken, Susan, Wakeham, Andrew C., Itie-Youten, Annick, Blencowe, Benjamin J., Mak, Tak W.
Publicado 2010

2-Methoxyestradiol inhibits experimental autoimmune encephalomyelitis through suppression of immune cell activation

por Duncan, Gordon S., Brenner, Dirk, Tusche, Michael W., Brüstle, Anne, Knobbe, Christiane B., Elia, Andrew J., Mock, Thomas, Bray, Mark R., Krammer, Peter H., Mak, Tak W.
Publicado 2012

Identification of BERP (brain-expressed RING finger protein) as a p53 target gene that modulates seizure susceptibility through interacting with GABA(A) receptors

por Cheung, Carol C., Yang, Caimei, Berger, Thorsten, Zaugg, Kathrin, Reilly, Patrick, Elia, Andrew J., Wakeham, Andrew, You-Ten, Annick, Chang, Ning, Li, Lijun, Wan, Qi, Mak, Tak Wah
Publicado 2010

E3 ubiquitin ligase Mule targets β-catenin under conditions of hyperactive Wnt signaling

por Dominguez-Brauer, Carmen, Khatun, Rahima, Elia, Andrew J., Thu, Kelsie L., Ramachandran, Parameswaran, Baniasadi, Shakiba P., Hao, Zhenyue, Jones, Lisa D., Haight, Jillian, Sheng, Yi, Mak, Tak W.
Publicado en Proc Natl Acad Sci U S A (2017)

Interleukin 13 Is Secreted by and Stimulates the Growth of Hodgkin and Reed-Sternberg Cells

por Kapp, Ursula, Yeh, Wen-Chen, Patterson, Bruce, Elia, Andrew J., Kägi, David, Ho, Alexandra, Hessel, Andrew, Tipsword, Mike, Williams, Alexia, Mirtsos, Christine, Itie, Annick, Moyle, Matthew, Mak, Tak W.
Publicado 1999

Acidic nuclear phosphoprotein 32kDa (ANP32)B-deficient mouse reveals a hierarchy of ANP32 importance in mammalian development

por Reilly, Patrick T., Afzal, Samia, Gorrini, Chiara, Lui, Koren, Bukhman, Yury V., Wakeham, Andrew, Haight, Jillian, Ling, Teo Wei, Cheung, Carol C., Elia, Andrew J., Turner, Patricia V., Mak, Tak Wah
Publicado 2011

Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-κB-dependent gene transcription

por Bonnard, Madeleine, Mirtsos, Christine, Suzuki, Shinobu, Graham, Kevin, Huang, Jianing, Ng, Michelle, Itié, Annick, Wakeham, Andrew, Shahinian, Arda, Henzel, William J., Elia, Andrew J., Shillinglaw, Wendy, Mak, Tak W., Cao, Zhaodan, Yeh, Wen-Chen
Publicado 2000

Chk2 Is a Tumor Suppressor That Regulates Apoptosis in both an Ataxia Telangiectasia Mutated (ATM)-Dependent and an ATM-Independent Manner

por Hirao, Atsushi, Cheung, Alison, Duncan, Gordon, Girard, Pierre-Marie, Elia, Andrew J., Wakeham, Andrew, Okada, Hitoshi, Sarkissian, Talin, Wong, Jorge A., Sakai, Takashi, de Stanchina, Elisa, Bristow, Robert G., Suda, Toshio, Lowe, Scott W., Jeggo, Penny A., Elledge, Stephen J., Mak, Tak W.
Publicado 2002

TAp73 is required for spermatogenesis and the maintenance of male fertility

por Inoue, Satoshi, Tomasini, Richard, Rufini, Alessandro, Elia, Andrew J., Agostini, Massimiliano, Amelio, Ivano, Cescon, Dave, Dinsdale, David, Zhou, Lily, Harris, Isaac S., Lac, Sophie, Silvester, Jennifer, Li, Wanda Y., Sasaki, Masato, Haight, Jillian, Brüstle, Anne, Wakeham, Andrew, Mckerlie, Colin, Jurisicova, Andrea, Melino, Gerry, Mak, Tak W.
Publicado 2014

D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function

por Sasaki, Masato, Knobbe, Christiane B., Itsumi, Momoe, Elia, Andrew J., Harris, Isaac S., Chio, Iok In Christine, Cairns, Rob A., McCracken, Susan, Wakeham, Andrew, Haight, Jillian, Ten, Annick You, Snow, Bryan, Ueda, Takeshi, Inoue, Satoshi, Yamamoto, Kazuo, Ko, Myunggon, Rao, Anjana, Yen, Katharine E., Su, Shinsan M., Mak, Tak Wah
Publicado 2012

Choline acetyltransferase-expressing T cells are required to control chronic viral infection

por Cox, Maureen A., Duncan, Gordon S., Lin, Gloria H. Y., Steinberg, Benjamin E., Yu, Lisa X., Brenner, Dirk, Buckler, Luke N., Elia, Andrew J., Wakeham, Andrew C., Nieman, Brian, Dominguez-Brauer, Carmen, Elford, Alisha R., Gill, Kyle T., Kubli, Shawn P., Haight, Jillian, Berger, Thorsten, Ohashi, Pamela S., Tracey, Kevin J., Olofsson, Peder S., Mak, Tak W.
Publicado en Science (2019)

BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival

por Gorrini, Chiara, Baniasadi, Pegah S., Harris, Isaac S., Silvester, Jennifer, Inoue, Satoshi, Snow, Bryan, Joshi, Purna A., Wakeham, Andrew, Molyneux, Sam D., Martin, Bernard, Bouwman, Peter, Cescon, David W., Elia, Andrew J., Winterton-Perks, Zoe, Cruickshank, Jennifer, Brenner, Dirk, Tseng, Alan, Musgrave, Melinda, Berman, Hal K., Khokha, Rama, Jonkers, Jos, Mak, Tak W., Gauthier, Mona L.
Publicado 2013