Different Toll-Like Receptor Stimuli Have a Profound Impact on Cytokines Required to Break Tolerance and Induce Autoimmunity

Por Lin, Albert C. C., Dissanayake, Dilan, Dhanji, Salim, Elford, Alisha R., Ohashi, Pamela S.
Publicado em 2011

Peptide-Pulsed Dendritic Cells Have Superior Ability to Induce Immune-Mediated Tissue Destruction Compared to Peptide with Adjuvant

Por Dissanayake, Dilan, Murakami, Kiichi, Tran, Michael D., Elford, Alisha R., Millar, Douglas G., Ohashi, Pamela S.
Publicado em 2014

CARD6 Is Interferon Inducible but Not Involved in Nucleotide-Binding Oligomerization Domain Protein Signaling Leading to NF-κB Activation

Por Dufner, Almut, Duncan, Gordon S., Wakeham, Andrew, Elford, Alisha R., Hall, Håkan T., Ohashi, Pamela S., Mak, Tak W.
Publicado em 2008

TNF-α is critical for antitumor but not antiviral T cell immunity in mice

Por Calzascia, Thomas, Pellegrini, Marc, Hall, Håkan, Sabbagh, Laurent, Ono, Nobuyuki, Elford, Alisha R., Mak, Tak W., Ohashi, Pamela S.
Publicado em 2007

CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity

Por Calzascia, Thomas, Pellegrini, Marc, Lin, Albert, Garza, Kristine M., Elford, Alisha R., Shahinian, Arda, Ohashi, Pamela S., Mak, Tak W.
Publicado em 2008

Transgenic expression of Hsc70 in pancreatic islets enhances autoimmune diabetes in response to β-cell damage.

Por Alam, Masih-ul, Harken, Julie A., Knorn, Anna-Maria, Elford, Alisha R., Wigmore, Kip, Ohashi, Pamela S., Millar, Douglas G.
Publicado em 2009

Caspase-3-Dependent β-Cell Apoptosis in the Initiation of Autoimmune Diabetes Mellitus

Por Liadis, Nicole, Murakami, Kiichi, Eweida, Mohamed, Elford, Alisha R., Sheu, Laura, Gaisano, Herbert Y., Hakem, Razqallah, Ohashi, Pamela S., Woo, Minna
Publicado em 2005

Tumor Growth Enhances Cross-Presentation Leading to Limited T Cell Activation without Tolerance

Por Nguyen, Linh T., Elford, Alisha R., Murakami, Kiichi, Garza, Kristine M., Schoenberger, Stephen P., Odermatt, Bernhard, Speiser, Daniel E., Ohashi, Pamela S.
Publicado em 2002

Exposure to sequestered self-antigens in vivo is not sufficient for the induction of autoimmune diabetes

Por Ono, Nobuyuki, Murakami, Kiichi, Chan, Olivia, Hall, Håkan, Elford, Alisha R., Yen, Patty, Calzascia, Thomas, Spencer, David M., Ohashi, Pamela S., Dhanji, Salim
Publicado no PLoS One (2017)

Hypoxia-inducible factor 1 alpha limits dendritic cell stimulation of CD8 T cell immunity

Por Tran, Charles W., Gold, Matthew J., Garcia-Batres, Carlos, Tai, Kelly, Elford, Alisha R., Himmel, Megan E., Elia, Andrew J., Ohashi, Pamela S.
Publicado no PLoS One (2020)

PKCθ Signals Activation versus Tolerance In Vivo

Por Berg-Brown, Nancy N., Gronski, Matthew A., Jones, Russell G., Elford, Alisha R., Deenick, Elissa K., Odermatt, Bernhard, Littman, Dan R., Ohashi, Pamela S.
Publicado em 2004

Cellular and Molecular Requirements for the Selection of in vitro-Generated CD8 T Cells Reveals a Role for Notch()

Por Dervovic, Dzana D., Liang, Haydn C-Y., Cannons, Jennifer L., Elford, Alisha R., Mohtashami, Mahmood, Ohashi, Pamela S., Schwartzberg, Pamela L., Zúñiga-Pflücker, Juan Carlos
Publicado em 2013

Overproduction of IL-2 by Cbl-b deficient CD4(+) T cells provides resistance against regulatory T cells

Por Han, SeongJun, Chung, Douglas C., St. Paul, Michael, Liu, Zhe Qi, Garcia-Batres, Carlos, Elford, Alisha R., Tran, Charles W., Chapatte, Laurence, Ohashi, Pamela S.
Publicado no Oncoimmunology (2020)

CD28-dependent Activation of Protein Kinase B/Akt Blocks Fas-mediated Apoptosis by Preventing Death-inducing Signaling Complex Assembly

Por Jones, Russell G., Elford, Alisha R., Parsons, Michael J., Wu, Linda, Krawczyk, Connie M., Yeh, Wen-Chen, Hakem, Razqallah, Rottapel, Robert, Woodgett, James R., Ohashi, Pamela S.
Publicado em 2002

Cellular FLICE-inhibitory protein is required for T cell survival and cycling

Por Chau, Hien, Wong, Veronica, Chen, Nien-Jung, Huang, Huey-Lan, Lin, Wen-Jye, Mirtsos, Christine, Elford, Alisha R., Bonnard, Madeleine, Wakeham, Andrew, You-Ten, Annick Itie, Lemmers, Bénédicte, Salmena, Leonardo, Pellegrini, Marc, Hakem, Razq, Mak, Tak W., Ohashi, Pamela, Yeh, Wen-Chen
Publicado em 2005

Development of an adoptive cell therapy protocol with tumor-infiltrating lymphocytes and intermediate-dose interleukin-2 therapy

Por Nguyen, Linh T, Butler, Marcus O, Yen, Pei Hua, Nie, Jessica, Pniak, Michael, Elford, Alisha R, Joshua, Anthony M, Hogg, David, Ghazarian, Danny, Al-Habeeb, Ayman, Easson, Alexandra M, Leong, Wey L, McCready, David R, Reedijk, Michael, Messner, Hans A, Ohashi, Pamela S
Publicado em 2013

NK Cells Regulate CD8(+) T Cell Mediated Autoimmunity

Por Lang, Philipp A., Crome, Sarah Q., Xu, Haifeng C., Lang, Karl S., Chapatte, Laurence, Deenick, Elissa K., Grusdat, Melanie, Pandyra, Aleksandra A., Pozdeev, Vitaly I., Wang, Ruifeng, Holderried, Tobias A. W., Cantor, Harvey, Diefenbach, Andreas, Elford, Alisha R., McIlwain, David R., Recher, Mike, Häussinger, Dieter, Mak, Tak W., Ohashi, Pamela S.
Publicado no Front Cell Infect Microbiol (2020)

Choline acetyltransferase-expressing T cells are required to control chronic viral infection

Por Cox, Maureen A., Duncan, Gordon S., Lin, Gloria H. Y., Steinberg, Benjamin E., Yu, Lisa X., Brenner, Dirk, Buckler, Luke N., Elia, Andrew J., Wakeham, Andrew C., Nieman, Brian, Dominguez-Brauer, Carmen, Elford, Alisha R., Gill, Kyle T., Kubli, Shawn P., Haight, Jillian, Berger, Thorsten, Ohashi, Pamela S., Tracey, Kevin J., Olofsson, Peder S., Mak, Tak W.
Publicado no Science (2019)

Loss of the signaling adaptor TRAF1 causes CD8(+) T cell dysregulation during human and murine chronic infection

Por Wang, Chao, McPherson, Ann J., Jones, R. Brad, Kawamura, Kim S., Lin, Gloria H.Y., Lang, Philipp A., Ambagala, Thanuja, Pellegrini, Marc, Calzascia, Thomas, Aidarus, Nasra, Elford, Alisha R., Yue, Feng Yun, Kremmer, Elisabeth, Kovacs, Colin M., Benko, Erika, Tremblay, Cecile, Routy, Jean-Pierre, Bernard, Nicole F., Ostrowski, Mario A., Ohashi, Pamela S., Watts, Tania H.
Publicado em 2012

Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8(+) T-cell immunity

Por Lang, Philipp A., Lang, Karl S., Xu, Haifeng C., Grusdat, Melanie, Parish, Ian A., Recher, Mike, Elford, Alisha R., Dhanji, Salim, Shaabani, Namir, Tran, Charles W., Dissanayake, Dilan, Rahbar, Ramtin, Ghazarian, Magar, Brüstle, Anne, Fine, Jason, Chen, Peter, Weaver, Casey T., Klose, Christoph, Diefenbach, Andreas, Häussinger, Dieter, Carlyle, James R., Kaech, Susan M., Mak, Tak W., Ohashi, Pamela S.
Publicado em 2012