Generation and Characterization of the Anp32e-Deficient Mouse

Tekijä Reilly, Patrick T., Afzal, Samia, Wakeham, Andrew, Haight, Jillian, You-Ten, Annick, Zaugg, Kathrin, Dembowy, Joanna, Young, Ashley, Mak, Tak W.
Julkaistu 2010

E3 ubiquitin ligase Mule targets β-catenin under conditions of hyperactive Wnt signaling

Tekijä Dominguez-Brauer, Carmen, Khatun, Rahima, Elia, Andrew J., Thu, Kelsie L., Ramachandran, Parameswaran, Baniasadi, Shakiba P., Hao, Zhenyue, Jones, Lisa D., Haight, Jillian, Sheng, Yi, Mak, Tak W.
Julkaisussa Proc Natl Acad Sci U S A (2017)

Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo

Tekijä Kamizono, Shintaro, Duncan, Gordon S., Seidel, Markus G., Morimoto, Akira, Hamada, Koichi, Grosveld, Gerard, Akashi, Koichi, Lind, Evan F., Haight, Jillian P., Ohashi, Pamela S., Look, A. Thomas, Mak, Tak W.
Julkaistu 2009

Acidic nuclear phosphoprotein 32kDa (ANP32)B-deficient mouse reveals a hierarchy of ANP32 importance in mammalian development

Tekijä Reilly, Patrick T., Afzal, Samia, Gorrini, Chiara, Lui, Koren, Bukhman, Yury V., Wakeham, Andrew, Haight, Jillian, Ling, Teo Wei, Cheung, Carol C., Elia, Andrew J., Turner, Patricia V., Mak, Tak Wah
Julkaistu 2011

Concerted roles of PTEN and ATM in controlling hematopoietic stem cell fitness and dormancy

Tekijä Fortin, Jerome, Bassi, Christian, Ramachandran, Parameswaran, Li, Wanda Y., Tian, Ruxiao, Zarrabi, Ida, Hill, Graham, Snow, Bryan E., Haight, Jillian, Tobin, Chantal, Hodgson, Kelsey, Wakeham, Andrew, Stambolic, Vuk, Mak, Tak W.
Julkaisussa J Clin Invest (2021)

Fas Receptor Expression in Germinal-Center B Cells Is Essential for T and B Lymphocyte Homeostasis

Tekijä Hao, Zhenyue, Duncan, Gordon S., Seagal, Jane, Su, Yu-Wen, Hong, Claire, Haight, Jillian, Chen, Nien-Jung, Elia, Andrew, Wakeham, Andrew, Li, Wanda Y., Liepa, Jennifer, Wood, Geoffrey A., Casola, Stefano, Rajewsky, Klaus, Mak, Tak W.
Julkaistu 2008

Autophagy-independent functions of UVRAG are essential for peripheral naive T-cell homeostasis

Tekijä Afzal, Samia, Hao, Zhenyue, Itsumi, Momoe, Abouelkheer, Yasser, Brenner, Dirk, Gao, Yunfei, Wakeham, Andrew, Hong, Claire, Li, Wanda Y., Sylvester, Jennifer, Gilani, Syed O., Brüstle, Anne, Haight, Jillian, You-Ten, Annick J., Lin, Gloria H. Y., Inoue, Satoshi, Mak, Tak W.
Julkaisussa Proc Natl Acad Sci U S A (2015)

DIPG-13. A NOVEL MOUSE MODEL REVEALS UNEXPECTED MECHANISMS OF ACTION OF ACVR1 MUTATIONS IN DIFFUSE INTRINSIC PONTINE GLIOMA

Tekijä Fortin, Jerome, Tian, Ruxiao, Zarrabi, Ida, Hill, Graham, Williams, Eleanor, Sanchez-Duffhues, Gonzalo, Thorikay, Midory, Ramachandran, Parameswaran, Siddaway, Robert, Wong, Jong, Haight, Jillian, You-Ten, Annick, Snow, Bryan, Wakeham, Andrew, Schramek, Daniel, Bullock, Alex, Dijke, Peter ten, Hawkins, Cynthia, Mak, Tak
Julkaisussa Neuro Oncol (2019)

Fcmr regulates mononuclear phagocyte control of anti-tumor immunity

Tekijä Kubli, Shawn P., Vornholz, Larsen, Duncan, Gordon, Zhou, Wenjing, Ramachandran, Parameswaran, Fortin, Jerome, Cox, Maureen, Han, SeongJun, Nechanitzky, Robert, Nechanitzky, Duygu, Snow, Bryan E., Jones, Lisa, Li, Wanda Y., Haight, Jillian, Wakeham, Andrew, Bray, Mark R., Mak, Tak W.
Julkaisussa Nat Commun (2019)

Author Correction: Fcmr regulates mononuclear phagocyte control of anti-tumor immunity

Tekijä Kubli, Shawn P., Vornholz, Larsen, Duncan, Gordon, Zhou, Wenjing, Ramachandran, Parameswaran, Fortin, Jerome, Cox, Maureen, Han, SeongJun, Nechanitzky, Robert, Nechanitzky, Duygu, Snow, Bryan E., Jones, Lisa, Li, Wanda Y., Haight, Jillian, Wakeham, Andrew, Bray, Mark R., Mak, Tak W.
Julkaisussa Nat Commun (2019)

TAp73 is required for spermatogenesis and the maintenance of male fertility

Tekijä Inoue, Satoshi, Tomasini, Richard, Rufini, Alessandro, Elia, Andrew J., Agostini, Massimiliano, Amelio, Ivano, Cescon, Dave, Dinsdale, David, Zhou, Lily, Harris, Isaac S., Lac, Sophie, Silvester, Jennifer, Li, Wanda Y., Sasaki, Masato, Haight, Jillian, Brüstle, Anne, Wakeham, Andrew, Mckerlie, Colin, Jurisicova, Andrea, Melino, Gerry, Mak, Tak W.
Julkaistu 2014

D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function

Tekijä Sasaki, Masato, Knobbe, Christiane B., Itsumi, Momoe, Elia, Andrew J., Harris, Isaac S., Chio, Iok In Christine, Cairns, Rob A., McCracken, Susan, Wakeham, Andrew, Haight, Jillian, Ten, Annick You, Snow, Bryan, Ueda, Takeshi, Inoue, Satoshi, Yamamoto, Kazuo, Ko, Myunggon, Rao, Anjana, Yen, Katharine E., Su, Shinsan M., Mak, Tak Wah
Julkaistu 2012

K48-linked KLF4 ubiquitination by E3 ligase Mule controls T-cell proliferation and cell cycle progression

Tekijä Hao, Zhenyue, Sheng, Yi, Duncan, Gordon S., Li, Wanda Y., Dominguez, Carmen, Sylvester, Jennifer, Su, Yu-Wen, Lin, Gloria H.Y., Snow, Bryan E., Brenner, Dirk, You-Ten, Annick, Haight, Jillian, Inoue, Satoshi, Wakeham, Andrew, Elford, Alisha, Hamilton, Sara, Liang, Yi, Zúñiga-Pflücker, Juan C., He, Housheng Hansen, Ohashi, Pamela S., Mak, Tak W.
Julkaisussa Nat Commun (2017)

Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas

Tekijä Fortin, Jerome, Tian, Ruxiao, Zarrabi, Ida, Hill, Graham, Williams, Eleanor, Sanchez-Duffhues, Gonzalo, Thorikay, Midory, Ramachandran, Parameswaran, Siddaway, Robert, Wong, Jong Fu, Wu, Annette, Apuzzo, Lorraine N., Haight, Jillian, You-Ten, Annick, Snow, Bryan E., Wakeham, Andrew, Goldhamer, David J., Schramek, Daniel, Bullock, Alex N., Dijke, Peter ten, Hawkins, Cynthia, Mak, Tak W.
Julkaisussa Cancer Cell (2020)

Choline acetyltransferase-expressing T cells are required to control chronic viral infection

Tekijä Cox, Maureen A., Duncan, Gordon S., Lin, Gloria H. Y., Steinberg, Benjamin E., Yu, Lisa X., Brenner, Dirk, Buckler, Luke N., Elia, Andrew J., Wakeham, Andrew C., Nieman, Brian, Dominguez-Brauer, Carmen, Elford, Alisha R., Gill, Kyle T., Kubli, Shawn P., Haight, Jillian, Berger, Thorsten, Ohashi, Pamela S., Tracey, Kevin J., Olofsson, Peder S., Mak, Tak W.
Julkaisussa Science (2019)

IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics

Tekijä Sasaki, Masato, Knobbe, Christiane B., Munger, Joshua C., Lind, Evan F., Brenner, Dirk, Brüstle, Anne, Harris, Isaac S., Holmes, Roxanne, Wakeham, Andrew, Haight, Jillian, You-Ten, Annick, Li, Wanda Y., Schalm, Stefanie, Su, Shinsan M., Virtanen, Carl, Reifenberger, Guido, Ohashi, Pamela S., Barber, Dwayne L., Figueroa, Maria E., Melnick, Ari, Zúñiga-Pflücker, Juan-Carlos, Mak, Tak W.
Julkaistu 2012

The E3 ubiquitin ligase Mule acts through the ATM–p53 axis to maintain B lymphocyte homeostasis

Tekijä Hao, Zhenyue, Duncan, Gordon S., Su, Yu-Wen, Li, Wanda Y., Silvester, Jennifer, Hong, Claire, You, Han, Brenner, Dirk, Gorrini, Chiara, Haight, Jillian, Wakeham, Andrew, You-Ten, Annick, McCracken, Susan, Elia, Andrew, Li, Qinxi, Detmar, Jacqui, Jurisicova, Andrea, Hobeika, Elias, Reth, Michael, Sheng, Yi, Lang, Philipp A., Ohashi, Pamela S., Zhong, Qing, Wang, Xiaodong, Mak, Tak W.
Julkaistu 2012

Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15

Tekijä Inoue, Satoshi, Hao, Zhenyue, Elia, Andrew J., Cescon, David, Zhou, Lily, Silvester, Jennifer, Snow, Bryan, Harris, Isaac S., Sasaki, Masato, Li, Wanda Y., Itsumi, Momoe, Yamamoto, Kazuo, Ueda, Takeshi, Dominguez-Brauer, Carmen, Gorrini, Chiara, Chio, Iok In Christine, Haight, Jillian, You-Ten, Annick, McCracken, Susan, Wakeham, Andrew, Ghazarian, Danny, Penn, Linda J.Z., Melino, Gerry, Mak, Tak W.
Julkaistu 2013

Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation

Tekijä Dominguez-Brauer, Carmen, Hao, Zhenyue, Elia, Andrew J., Fortin, Jérôme M., Nechanitzky, Robert, Brauer, Patrick M., Sheng, Yi, Mana, Miyeko D., Chio, Iok In Christine, Haight, Jillian, Pollett, Aaron, Cairns, Robert, Tworzyanski, Leanne, Inoue, Satoshi, Reardon, Colin, Marques, Ana, Silvester, Jennifer, Cox, Maureen A., Wakeham, Andrew, Yilmaz, Omer H., Sabatini, David M., van Es, Johan H., Clevers, Hans, Sato, Toshiro, Mak, Tak W.
Julkaisussa Cell Stem Cell (2016)

Involvement of Toso in activation of monocytes, macrophages, and granulocytes

Tekijä Lang, Karl S., Lang, Philipp A., Meryk, Andreas, Pandyra, Aleksandra A., Boucher, Louis-Martin, Pozdeev, Vitaly I., Tusche, Michael W., Göthert, Joachim R., Haight, Jillian, Wakeham, Andrew, You-Ten, Annick J., McIlwain, David R., Merches, Katja, Khairnar, Vishal, Recher, Mike, Nolan, Garry P., Hitoshi, Yasumichi, Funkner, Pauline, Navarini, Alexander A., Verschoor, Admar, Shaabani, Namir, Honke, Nadine, Penn, Linda Z., Ohashi, Pamela S., Häussinger, Dieter, Lee, Kyeong-Hee, Mak, Tak W.
Julkaistu 2013