CBL Linker Region and RING Finger Mutations Lead to Enhanced Granulocyte-Macrophage Colony-stimulating Factor (GM-CSF) Signaling via Elevated Levels of JAK2 and LYN

Por Javadi, Mojib, Richmond, Terri D., Huang, Kai, Barber, Dwayne L.
Publicado em 2013

STAT1 promotes megakaryopoiesis downstream of GATA-1 in mice

Por Huang, Zan, Richmond, Terri D., Muntean, Andrew G., Barber, Dwayne L., Weiss, Mitchell J., Crispino, John D.
Publicado em 2007

Tyrosine kinase chromosomal translocations mediate distinct and overlapping gene regulation events

Por Kim, Hani, Gillis, Lisa C, Jarvis, Jordan D, Yang, Stuart, Huang, Kai, Der, Sandy, Barber, Dwayne L
Publicado em 2011

The SH2B1 Adaptor Protein Associates with a Proximal Region of the Erythropoietin Receptor

Por Javadi, Mojib, Hofstätter, Edda, Stickle, Natalie, Beattie, Bryan K., Jaster, Robert, Carter-Su, Christin, Barber, Dwayne L.
Publicado em 2012

Random Mutagenesis Reveals Residues of JAK2 Critical in Evading Inhibition by a Tyrosine Kinase Inhibitor

Por Marit, Michael R., Chohan, Manprit, Matthew, Natasha, Huang, Kai, Kuntz, Douglas A., Rose, David R., Barber, Dwayne L.
Publicado em 2012

Src homology 2 domain–containing inositol 5-phosphatase 1 deficiency leads to a spontaneous allergic inflammation in the murine lung

Por Oh, Sun-Young, Zheng, Tao, Bailey, Monica L., Barber, Dwayne L., Schroeder, John T., Kim, Yoon-Keun, Zhu, Zhou
Publicado no J Allergy Clin Immunol (2006)

TRPC3 Is the Erythropoietin-regulated Calcium Channel in Human Erythroid Cells

Por Tong, Qin, Hirschler-Laszkiewicz, Iwona, Zhang, Wenyi, Conrad, Kathleen, Neagley, David W., Barber, Dwayne L., Cheung, Joseph Y., Miller, Barbara A.
Publicado em 2008

TRPC3 Activation by Erythropoietin Is Modulated by TRPC6

Por Hirschler-Laszkiewicz, Iwona, Tong, Qin, Conrad, Kathleen, Zhang, Wenyi, Flint, Wesley W., Barber, Alistair J., Barber, Dwayne L., Cheung, Joseph Y., Miller, Barbara A.
Publicado em 2009

Preclinical validation: LV/IL-12 transduction of patient leukemia cells for immunotherapy of AML

Por Huang, Ju, Liu, Yuanfeng, Au, Bryan C, Barber, Dwayne L, Arruda, Andrea, Schambach, Axel, Rothe, Michael, Minden, Mark D, Paige, Christopher J, Medin, Jeffrey A
Publicado no Mol Ther Methods Clin Dev (2016)

Ibrutinib synergizes with poly(ADP-ribose) glycohydrolase inhibitors to induce cell death in AML cells via a BTK-independent mechanism

Por Rotin, Lianne E., Gronda, Marcela, MacLean, Neil, Hurren, Rose, Wang, XiaoMing, Lin, Feng-Hsu, Wrana, Jeff, Datti, Alessandro, Barber, Dwayne L., Minden, Mark D., Slassi, Malik, Schimmer, Aaron D.
Publicado no Oncotarget (2015)

Cytopenia induction by 5-fluorouracil identifies thrombopoietic mutants in sensitized ENU mutagenesis screens

Por Anderson, Nicole M., Berberovic, Zorana, Berndl, Elizabeth, Bailey, Monica L., Flenniken, Ann M., Osborne, Lucy R., Adamson, S. Lee, Rossant, Janet, Wang, Chen, Minden, Mark D., McNagny, Kelly M., Paulson, Robert F., Barber, Dwayne L., Stanford, William L.
Publicado em 2011

Enu Mutagenesis Identifies a Novel Platelet Phenotype in a Loss-Of-Function Jak2 Allele

Por Anderson, Nicole M., Javadi, Mojib, Berndl, Elizabeth, Berberovic, Zorana, Bailey, Monica L., Huang, Kai, Flenniken, Ann M., Osborne, Lucy R., Adamson, S. Lee, Rossant, Janet, Carter-Su, Christin, Wang, Chen, McNagny, Kelly M., Paulson, Robert F., Minden, Mark D., Stanford, William L., Barber, Dwayne L.
Publicado em 2013

A novel ENU-generated truncation mutation lacking the spectrin-binding and C-terminal regulatory domains of Ank1 models severe hemolytic hereditary spherocytosis

Por Hughes, Michael R., Anderson, Nicole, Maltby, Steven, Wong, Justin, Berberovic, Zorana, Birkenmeier, Connie S., Haddon, D. James, Garcha, Kamal, Flenniken, Ann, Osborne, Lucy R., Adamson, S. Lee, Rossant, Janet, Peters, Luanne L., Minden, Mark D., Paulson, Robert F., Wang, Chen, Barber, Dwayne L., McNagny, Kelly M., Stanford, William L.
Publicado em 2010

LOSS OF JAK2 REGULATION VIA VHL-SOCS1 E3 UBIQUITIN HETEROCOMPLEX UNDERLIES CHUVASH POLYCYTHEMIA

Por Russell, Ryan C., Sufan, Roxana I., Zhou, Bing, Heir, Pardeep, Bunda, Severa, Sybingco, Stephanie S., Greer, Samantha N., Roche, Olga, Heathcote, Samuel A., Chow, Vinca W.K., Boba, Lukasz M., Richmond, Terri D., Hickey, Michele M., Barber, Dwayne L., Cheresh, David A., Simon, M. Celeste, Irwin, Meredith S., Kim, William Y., Ohh, Michael
Publicado em 2011

IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics

Por Sasaki, Masato, Knobbe, Christiane B., Munger, Joshua C., Lind, Evan F., Brenner, Dirk, Brüstle, Anne, Harris, Isaac S., Holmes, Roxanne, Wakeham, Andrew, Haight, Jillian, You-Ten, Annick, Li, Wanda Y., Schalm, Stefanie, Su, Shinsan M., Virtanen, Carl, Reifenberger, Guido, Ohashi, Pamela S., Barber, Dwayne L., Figueroa, Maria E., Melnick, Ari, Zúñiga-Pflücker, Juan-Carlos, Mak, Tak W.
Publicado em 2012

Lentivector Iterations and Pre-Clinical Scale-Up/Toxicity Testing: Targeting Mobilized CD34(+) Cells for Correction of Fabry Disease

Por Huang, Ju, Khan, Aneal, Au, Bryan C., Barber, Dwayne L., López-Vásquez, Lucía, Prokopishyn, Nicole L., Boutin, Michel, Rothe, Michael, Rip, Jack W., Abaoui, Mona, Nagree, Murtaza S., Dworski, Shaalee, Schambach, Axel, Keating, Armand, West, Michael L., Klassen, John, Turner, Patricia V., Sirrs, Sandra, Rupar, C. Anthony, Auray-Blais, Christiane, Foley, Ronan, Medin, Jeffrey A.
Publicado no Mol Ther Methods Clin Dev (2017)

Lentivirus-mediated gene therapy for Fabry disease

Por Khan, Aneal, Barber, Dwayne L., Huang, Ju, Rupar, C. Anthony, Rip, Jack W., Auray-Blais, Christiane, Boutin, Michel, O’Hoski, Pamela, Gargulak, Kristy, McKillop, William M., Fraser, Graeme, Wasim, Syed, LeMoine, Kaye, Jelinski, Shelly, Chaudhry, Ahsan, Prokopishyn, Nicole, Morel, Chantal F., Couban, Stephen, Duggan, Peter R., Fowler, Daniel H., Keating, Armand, West, Michael L., Foley, Ronan, Medin, Jeffrey A.
Publicado no Nat Commun (2021)