The zinc finger domain of Wilms' tumor 1 suppressor gene (WT1) behaves as a dominant negative, leading to abrogation of WT1 oncogenic potential in breast cancer cells

Por Han, Youqi, San-Marina, Serban, Yang, Lin, Khoury, Haytham, Minden, Mark D
Publicado em 2007

Hematopoietic Cell Fate and the Initiation of Leukemic Properties in Primitive Primary Human Cells Are Influenced by Ras Activity and Farnesyltransferase Inhibition

Por Dorrell, Craig, Takenaka, Katsuto, Minden, Mark D., Hawley, Robert G., Dick, John E.
Publicado em 2004

Insights into acute myeloid leukemia via single cell network profiling

Por Kornblau, Steven M., Minden, Mark D., Hogge, Donna, Cohen, AileenC, Cesano, Alessandra
Publicado no Clin Lab Int (2010)

Cancer patient perceptions on the ethical and legal issues related to biobanking

Por Master, Zubin, Claudio, Jaime O, Rachul, Christen, Wang, Jean CY, Minden, Mark D, Caulfield, Timothy
Publicado em 2013

Health care crisis in Gaza

Por Schimmer, Aaron D., Malkin, David, Zackenhaus, Eldad, Kagal, Allan, Klip, Amira, Rotin, Daniela, Minden, Mark D., Teitel, Jerome
Publicado em 2009

Outcomes and Predictors of Mortality for Patients with Acute Leukemia Admitted to the Intensive Care Unit

Por Kraguljac, Alan P., Croucher, Danielle, Christian, Michael, Ibrahimova, Narmin, Kumar, Vikram, Jacob, Gabriella, Kiss, Alex, Minden, Mark D., Mehta, Sangeeta
Publicado no Can Respir J (2016)

Distinct Patterns of DNA Damage Response and Apoptosis Correlate with Jak/Stat and PI3Kinase Response Profiles in Human Acute Myelogenous Leukemia

Por Rosen, David B., Putta, Santosh, Covey, Todd, Huang, Ying-Wen, Nolan, Garry P., Cesano, Alessandra, Minden, Mark D., Fantl, Wendy J.
Publicado em 2010

Symptom burden and supportive care in patients with acute leukemia

Por Zimmermann, Camilla, Yuen, Dora, Mischitelle, Ashley, Minden, Mark D., Brandwein, Joseph M., Schimmer, Aaron, Gagliese, Lucia, Lo, Christopher, Rydall, Anne, Rodin, Gary
Publicado em 2013

Traumatic stress in acute leukemia

Por Rodin, Gary, Yuen, Dora, Mischitelle, Ashley, Minden, Mark D, Brandwein, Joseph, Schimmer, Aaron, Marmar, Charles, Gagliese, Lucia, Lo, Christopher, Rydall, Anne, Zimmermann, Camilla
Publicado em 2011

Anti leukemia effect of ex vivo expanded DNT cells from AML patients: a potential novel autologous T cell adoptive immunotherapy

Por Merims, Sharon, Li, Xujian, Joe, Betty, Dokouhaki, Pouneh, Han, Mei, Childs, Richard W., Wang, Zhen-yi, Gupta, Vikas, Minden, Mark D., Zhang, Li
Publicado em 2011

Tyrosine Phosphorylation of the Lyn Src Homology 2 (SH2) Domain Modulates Its Binding Affinity and Specificity

Por Jin, Lily L., Wybenga-Groot, Leanne E., Tong, Jiefei, Taylor, Paul, Minden, Mark D., Trudel, Suzanne, McGlade, C. Jane, Moran, Michael F.
Publicado no Mol Cell Proteomics (2015)

A novel isoflavone, ME-344, targets the cytoskeleton in acute myeloid leukemia

Por Jeyaraju, Danny V., Hurren, Rose, Wang, Xiaoming, MacLean, Neil, Gronda, Marcela, Shamas-Din, Aisha, Minden, Mark D., Giaever, Guri, Schimmer, Aaron D.
Publicado no Oncotarget (2016)

Functional Characterization of FLT3 Receptor Signaling Deregulation in Acute Myeloid Leukemia by Single Cell Network Profiling (SCNP)

Por Rosen, David B., Minden, Mark D., Kornblau, Steven M., Cohen, Aileen, Gayko, Urte, Putta, Santosh, Woronicz, John, Evensen, Erik, Fantl, Wendy J., Cesano, Alessandra
Publicado em 2010

Increased pressure alters plasma membrane dynamics and renders acute myeloid leukemia cells resistant to daunorubicin

Por Nirmalanandhan, Victor Sanjit, Hurren, Rose, Cameron, William D., Gronda, Marcela, Shamas-Din, Aisha, You, Lidan, Minden, Mark D., Rocheleau, Jonathan V., Schimmer, Aaron D
Publicado no Haematologica (2015)

Dynamic Single-Cell Network Profiles in Acute Myelogenous Leukemia Are Associated with Patient Response to Standard Induction Therapy

Por Kornblau, Steven M., Minden, Mark D., Rosen, David B., Putta, Santosh, Cohen, Aileen, Covey, Todd, Spellmeyer, David C., Fantl, Wendy J., Gayko, Urte, Cesano, Alessandra
Publicado em 2010

Preclinical validation: LV/IL-12 transduction of patient leukemia cells for immunotherapy of AML

Por Huang, Ju, Liu, Yuanfeng, Au, Bryan C, Barber, Dwayne L, Arruda, Andrea, Schambach, Axel, Rothe, Michael, Minden, Mark D, Paige, Christopher J, Medin, Jeffrey A
Publicado no Mol Ther Methods Clin Dev (2016)

Genomic characterization of pediatric T-cell acute lymphoblastic leukemia reveals novel recurrent driver mutations

Por Spinella, Jean-François, Cassart, Pauline, Richer, Chantal, Saillour, Virginie, Ouimet, Manon, Langlois, Sylvie, St-Onge, Pascal, Sontag, Thomas, Healy, Jasmine, Minden, Mark D., Sinnett, Daniel
Publicado no Oncotarget (2016)

Insulin receptor substrate 1 is a substrate of the Pim protein kinases

Por Song, Jin H., Padi, Sathish K. R., Luevano, Libia A., Minden, Mark D., DeAngelo, Daniel J., Hardiman, Gary, Ball, Lauren E., Warfel, Noel A., Kraft, Andrew S.
Publicado no Oncotarget (2016)

Metabolic Adaptation to Chronic Inhibition of Mitochondrial Protein Synthesis in Acute Myeloid Leukemia Cells

Por Jhas, Bozhena, Sriskanthadevan, Shrivani, Skrtic, Marko, Sukhai, Mahadeo A., Voisin, Veronique, Jitkova, Yulia, Gronda, Marcela, Hurren, Rose, Laister, Rob C., Bader, Gary D., Minden, Mark D., Schimmer, Aaron D.
Publicado em 2013

Ibrutinib synergizes with poly(ADP-ribose) glycohydrolase inhibitors to induce cell death in AML cells via a BTK-independent mechanism

Por Rotin, Lianne E., Gronda, Marcela, MacLean, Neil, Hurren, Rose, Wang, XiaoMing, Lin, Feng-Hsu, Wrana, Jeff, Datti, Alessandro, Barber, Dwayne L., Minden, Mark D., Slassi, Malik, Schimmer, Aaron D.
Publicado no Oncotarget (2015)