Functional Characterization of FLT3 Receptor Signaling Deregulation in Acute Myeloid Leukemia by Single Cell Network Profiling (SCNP)

BACKGROUND: Molecular characterization of the FMS-like tyrosine kinase 3 receptor (FLT3) in cytogenetically normal acute myeloid leukemia (AML) has recently been incorporated into clinical guidelines based on correlations between FLT3 internal tandem duplications (FLT3-ITD) and decreased disease-fre...

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Detalhes bibliográficos
Main Authors: Rosen, David B., Minden, Mark D., Kornblau, Steven M., Cohen, Aileen, Gayko, Urte, Putta, Santosh, Woronicz, John, Evensen, Erik, Fantl, Wendy J., Cesano, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965086/
https://ncbi.nlm.nih.gov/pubmed/21048955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013543
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